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JOURNAL CLUB
Collection of Commentaries on Veterinary, Medical, & Related Literature UROLOGY
CRITICAL POINTS
Interim Evaluation of the Efficacy and Safety of a High Dose Short Duration Enrofloxacin Treatment Regime for Urinary Tract Infection in Dogs Irom S, Westropp J, Chew D, Daniels J. Journal of Veterinary Internal Medicine
BCTUSBDU Management for canine urinary tract infections (UTIs)
r 5IJT TUVEZ EFUFSNJOFE XIFUIFS IJHI EPTF short-duration enrofloxacin therapy was as effi- cacious as standard antimicrobial protocol for canine UTIs.
r 4UVEZ EPHT XFSF TQMJU JOUP HSPVQT POF received enrofloxacin and the other received clavulanate.
VTVBMMZ JODMVEFT UP EBZT PG BOUJCJPUJD USFBUNFOU IPXFWFS compliance with these recommendations can be an issue. Short-duration fluoroquinolone dosing is often used in human medicine to treat uncomplicated UTIs. This study determined whether a high-dose, short-duration enrofloxacin treatment was equivalent in efficacy when compared with a standard UTI antimicrobial protocol. Client-owned adult dogs with naturally-occurring, uncomplicated UTIs were randomly BTTJHOFE UP PG USFBUNFOU HSPVQT
r 5IF SFTVMUT JOEJDBUFE UIBU IJHI EPTF TIPSU duration enrofloxacin is an effective treatment for uncomplicated canine UTIs.
UP NH LH PSBM FOSPGMPYBDJO 2 ) GPS EBZT BOE EPHT UP NH
LH PSBM BNPYJDJMMJO DMBWVMBOBUF 2 ) GPS EBZT #PUI HSPVQT IBE VSJOBMZTFT BOE VSJOF DVMUVSFT QFSGPSNFE PO EBZ BOE "U UIF UJNF PG JOUFSJN BOBMZTJT EPHT IBE DPNQMFUFE UIF USJBM #BDUFSJPMPHJD DVSF XBT BDIJFWFE JO USFBUFE XJUI FOSPGMPYBDJO BOE EPHT
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that the high-dose, short-duration enrofloxacin protocol was equally effective to the standard protocol in treatment for uncomplicated canine UTI.
Gregory F. Grauer, DVM, MS, Diplomate ACVIM (Small Animal Internal Medicine), Kansas State University
Editor's Note: It would have been interesting to expand the scope of this study and treat 2 groups of dogs with enrofloxacin, with 1 group receiving high-dose short-duration therapy and the other, lower-dose longer-duration therapy. Comparing 2 groups treated with the same antibiotic would have removed the variable of differing antibiotic sensitivities, allowing researchers to isolate and cleanly test the effect of dose and duration of enrofloxacin.
INFECTIOUS & ZOONOTIC DISEASE
Prevalence of Infectious Diseases in Cats and Dogs Rescued Following Hurricane Katrina Levy JK, Lappin MR, Glaser AL, et al. Journal of the American Veterinary Medical Association 2011; 238(3):311-316.
This article describes a cross-sectional study to determine the prevalence of infectious diseases with zoonotic
potential in animals rescued and relocated after Hurricane Katrina from the Gulf Coast area. Study animals included any cat or dog transferred from the disaster area from which blood or serum samples could be obtained: r EPHT XFSF UFTUFE GPS Anaplasma, Babesia, Bartonella, Borrelia borgdorferi, canine influenza virus (CIV), Dirofilaria immitis, Ehrlichia, Mycoplasma, Toxoplasma, West Nile virus (WNV), and Wolbachia.
r DBUT XFSF UFTUFE GPS Bartonella, Cytauxzoon, D immitis, Ehrlichia, feline immunodeficiency virus (FIV), feline leu- kemia virus (FeLV), Mycoplasma, Toxoplasma, WNV, and Wolbachia.
The results demonstrated that, based on the samples
obtained, cats and dogs relocated from the disaster area had evidence of multiple infectious diseases. r *O EPHT QSFWBMFODF XBT IJHIFTU GPS 8/7 tis
T gondii BOE '*7 BOE Mycoplasma
r *O DBUT QSFWBMFODF XBT IJHIFTU GPS Bartonella T gondii immitis
Mycoplasma 8/7
ical ranges for some of those diseases to nonendemic areas. Joel D. Ray, DVM, MS, Mississippi State University
D These results could be associated with expansion of geograph- D immi- CRITICAL POINTS
r 5IJT TUVEZ EFUFSNJOFE UIF QSFWBMFODF PG JOGFD- tious/zoonotic diseases in animals that were rescued and relocated after Hurricane Katrina.
r #MPPE BOE TFSVN TBNQMFT GSPN EPHT BOE DBUT XFSF UFTUFE GPS B WBSJFUZ PG EJTFBTFT
including Anaplasma, Babesia, Bartonella, B borgdorferi, CIV, Cytauxzoon, D immitis, Ehrlichia, FeLV, FIV, Mycoplasma, Toxoplasma, WNV, and Wolbachia.
r *O EPHT UIF IJHIFTU QSFWBMFODF XBT GPS 8/7 JO DBUT Bartonella
r 4IBSFE QSFWBMFODFT JODMVEFE D immitis, Mycoplasma, T gondii, and WNV.
January/February 2012 Today's Veterinary Practice
73