Today's Veterinary Practice

MAY-JUN 2017

Today's Veterinary Practice provides comprehensive information to keep every small animal practitioner up to date on companion animal medicine and surgery as well as practice building and management.

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soft chewable tablets Non-steroidal anti-inflammatory drug For oral use in dogs only BRIEF SUMMARY: Before using quellin soft chewable tablets, please consult the product insert, a summary of which follows: CAUTION: Federal Law restricts this drug to use by or on the order of a licensed veterinarian. PRODUCT DESCRIPTION: quellin (carprofen) is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes ibuprofen, naproxen, and ketoprofen. INDICATIONS: quellin is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs. CONTRAINDICATIONS: quellin should not be used in dogs exhibiting previous hypersensitivity to carprofen. WARNINGS: Keep out of reach of children. Not for human use. Consult a physician in cases of accidental ingestion by humans. For use in dogs only. Do not use in cats. All dogs should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data prior to, and periodically during, administration of any NSAID should be considered. PRECAUTIONS: As a class, NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity. Effects may result from decreased prostaglandin production and inhibition of the enzyme cyclooxygenase which is responsible for the formation of prostaglandins from arachindonic acid. When NSAIDs inhibit prostaglandins that cause inflammation they may also inhibit those prostaglandins which maintain normal homeostatic function. These antiprostaglandin effects may result in clinically significant disease in patients with underlying or pre-existing disease more often than in healthy patients. Carprofen is an NSAID, and as with others in that class, adverse reactions may occur with its use. The most frequently reported effects have been gastrointestinal signs. Events involving suspected renal, hematologic, and neurologic, dermatologic, and hepatic effects have also been reported. Concomitant use of carprofen with other anti-inflammatory drugs, such as other NSAIDs or corticosteroids, should be avoided because of the potential increase of adverse reactions, including gastrointestinal ulcerations and/or perforations. Carprofen is not recommended for use in dogs with bleeding disorders, as safety has not been established in dogs with these disorders. The safe use of carprofen in animals less than 6 weeks of age, pregnant dogs, dogs used for breeding purposes, or in lactating bitches has not been established. ADVERSE REACTIONS: During investigational studies for the caplet formulation with twice-daily administration of 1 mg/ lb., no clinically significant adverse reactions were reported. Some clinical signs were observed during field studies which were similar for carprofen caplet and placebo treated dogs. Incidences were observed in both groups: vomiting (4%), diarrhea (4%), changes in appetite (3%), lethargy (1.4%), behavioral changes (1%), and constipation (0.3%). For a copy of the Safety Data Sheet (SDS) or to report adverse reactions call Bayer Veterinary Services at 1-800-422-9874. For consumer questions call 1-800-255-6826. ANADA 200-555 Approved by FDA ©2015 Bayer HealthCare LLC. Bayer, the Bayer Cross and quellin are registered trademarks of Bayer. Bayer HealthCare LLC, Animal Health Division, PO Box 390, Shawnee Mission, KS 66201 December 2015 20042 BAY122815 (carprofen) ¨ quellin ® is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. WARNINGS: Keep out of reach of children. Not for human use. Consult a physician in cases of accidental ingestion by humans. For use in dogs only. Do not use in cats. ©2017 Bayer, Shawnee Mission, Kansas 66201. Bayer, the Bayer Cross and quellin are registered trademarks of Bayer. Take 30% off of quellin ® veterinary list prices through August 31, 2017. Applies to all SKU. Take two months to pay with net 60-day terms. Program Terms: Program eligibility is restricted to practices (including hospitals and clinics) with a licensed, practicing veterinarian on staff. Discounts will be paid only on products purchased for use by a practice or retail sale by a practice to clients in a bona fide veterinarian/client/practice relationship as defined by the American Veterinary Medical Association (AVMA). Failure to comply with these terms and conditions, and any other criteria of this discount may result in loss of the discount and/or make the practice ineligible for further participation in the program. Decisions with respect to eligibility and amount of discounts and payment are at the sole discretion of Bayer. All such decisions are final. Discounted product cannot be returned for any value in excess of the discounted purchase price. Bayer reserves the right to vary the terms and conditions of this program or to cancel this program upon notice through the BayerDVM.com website. Void where prohibited by law. QL17697 GOOD DOGS DESERVE (carprofen) ¨ 30 % ––– OFF ––– OF QUELLIN ® VETERINARY LIST PRICES THROUGH AUGUST 31, 2017. Contact your Bayer Sales Representative. quellinsoftchew.com Enticing meat flavor with no animal proteins Easy for dogs to chew Easy for owners to administer Scored for simple, accurate dosing

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