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PEER REVIEWED 40 CE: INFLAMMATORY BOWEL DISEASE 1. What is/are the most common cell infiltrate(s) within the lamina propria in IBD? a. Macrophages b. Eosinophils c. Neutrophils d. Lymphocytic and plasmacytic 2. Boxers and French bulldogs are suspected to have a predisposition for which chronic enteropathy? a. Histiocytic ulcerative colitis b. Lymphangiectasia c. Inflammatory bowel disease d. Immunoproliferative enteropathy 3. In German shepherds with IBD, there is thought to be single nucleotide polymorphisms in which Toll- like receptor (TLR)? a. TLR 3 b. TLR 4 c. TLR 8 d. TLR 9 4. The pathogenesis IBD is thought to be multifactorial; suspected etiologies include all of the following except: a. Genetics b. Dysbiosis c. Deficiencies in immune tolerance d. Immunosuppressive therapies 5. Which biochemical finding in dogs correlates with a negative outcome in IBD? a. Elevated alanine aminotransferase b. Elevated creatine kinase c. Hypokalemia d. Hypoalbuminemia 6. Deficiency of ________ should always be corrected in IBD patients, as failure to correct the deficiency can delay clinical improvement. a. Cobalamin b. Magnesemium c. Calcium d. Folate 7. Confirmation of a diagnosis of IBD involves which specific diagnostic test? a. Complete blood count b. Ultrasound with fine needle aspiration c. Endoscopy with histopathologic review of biopsy samples d. Serum chemistry 8. A positive response to a dietary trial with a hydrolysate or novel protein involves improvement within ______ weeks. a. 1 to 2 b. 4 to 6 c. 8 to 10 d. 12 to 15 9. In dogs with IBD refractory to prednisone therapy, which rescue immunosuppressive therapy has shown some proven beneficial response? a. Leflunomide b. Chlorambucil, single-drug therapy c. Azathioprine, single-drug therapy d. Cyclosporine 10. In cats, which combination of medications has shown successful control of IBD? a. Prednisone and cyclosporine b. Prednisolone and chlorambucil c. Prednisolone and mycophenolate d. Prednisolone and cyclosporine Inflammatory Bowel Disease in Dogs and Cats LEARNING OBJECTIVES By reading this article, participants will acquire a better knowledge base of the known pathogenesis of, and common clinical signs associated with, inflammatory bowel disease (IBD). Readers will also be able to methodically consider the differential diagnoses and diagnostic testing for chronic enteropathies, recognize when it may be best to refer for additional diagnostics, and establish an appropriate treatment plan. OVERVIEW This article provides an overview of the factors involved in canine and feline IBD, including the genetic, immune, environmental, and gastrointestinal interactions, as well as clinical findings, diagnosis, treatment options, and prognosis. The article you have read has been submitted for RACE approval for 1 hour of continuing education credit and will be opened for enrollment when approval has been received. To receive credit, take the approved test online for free at vetfolio.com/journal-ce . Free registration on VetFolio.com is required. Questions and answers online may differ from those below. Tests are valid for 2 years from the date of approval. CONTINUING EDUCATION NOTE Questions online may differ from those here; answers are available once CE test is taken at vetfolio.com/journal-ce . Tests are valid for 2 years from date of approval.