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PEER REVIEWED 58 CE: CANINE ATOPIC DERMATITIS 43. Dip R, Carmichael J, Letellier I, et al. Concurrent short-term use of prednisolone with cyclosporine A accelerates pruritus reduction and improvement in clinical scoring in dogs with atopic dermatitis. BMC Vet Res. 2013;9:173. 44. Panteri A, Strehlau G, Helbig R, et al. Repeated oral dose tolerance in dogs treated concomitantly with ciclosporin and oclacitinib for three weeks. Vet Dermatol 2016;27:22-e7. 45. McAtee BB, Cummings KJ, Cook AK, et al. Opportunistic invasive cutaneous fungal infections associated with administration of cyclosporine to dogs with immune-mediated disease. J Vet Intern Med 2017 Sep 9. 46. Peterson AL, Torres SM, Rendahl A, et al. Frequency of urinary tract infection in dogs with inflammatory skin disorders treated with ciclosporin alone or in combination with glucocorticoid therapy: a retrospective study. Vet Dermatol 2012;23:201-e43. 47. Steffan J, Strehlau G, Maurer M, et al. Cyclosporine A pharmacokinetics and efficacy in the treatment of atopic dermatitis in dogs. J Vet Pharmacol Ther 2004;27:231-238. 48. Kovalik M, Taszkun I, Pomorski Z, et al. Evaluation of a human generic formulation of ciclosporin in the treatment of canine atopic dermatitis with in vitro assessment of the functional capacity of phagocytic cells. Vet Rec 2011;168:537-542. 49. Navarro C, Crastes N, Benizeau E, et al. Voluntary acceptance and consumption of two oral ciclosporin formulations in dogs: two randomised, controlled studies. Ir Vet J 2015;68:3. 50. Archer TM, Boothe DM, Langston VC, et al. Oral cyclosporine treatment in dogs: a review of the literature. J Vet Intern Med 2014;28:1-20. 51. Michels GM, Ramsey DS, Walsh KF, et al. A blinded, randomized, placebo-controlled, dose determination trial of lokivetmab (ZTS- 00103289), a caninized, anti-canine IL-31 monoclonal antibody in client owned dogs with atopic dermatitis. Vet Dermatol 2016;27:478-e129. 3. Reactive treatment in atopic dermatitis means: a. Treatment is applied continuously with daily frequency b. Treatment is applied intermittently c. Treatment is applied twice weekly only on weekends (Saturday, Sunday) d. Treatment is applied only when clinical signs develop Canine Atopic Dermatitis: Updates on Diagnosis and Treatment 1. Oclacitinib is a novel a. Monoclonal antibody b. JAK inhibitor c. Glucocorticoid d. Calcineurin inhibitor 2. Which of the following lesions and sites would be likely to be present in dog affected by flea allergy dermatitis? a. Lichenification and scaling in the ventral neck b. Recurrent otitis externa c. Self-induced alopecia lumbosacral area, tail base, and caudomedial thighs d. Erythematous papules in the interdigital areas LEARNING OBJECTIVES After reading this article, practitioners should be able to determine which flare factors (or environmental conditions) are responsible for canine atopic dermatitis (CAD), a common chronic relapsing pruritic skin disease of dogs. The readers will recognize the importance of a rational diagnostic and multimodal therapeutic plan that provides the best management of this disease. Atopic dogs need to be evaluated regularly, and treatment plans should be modified for each patient, particularly with every flare of clinical signs. TOPIC OVERVIEW CAD is a chronic, incurable, but manageable inflammatory and pruritic disease of the skin. Medications used to treat allergic skin disease mask clinical signs but do not change the disease process unless allergen-specific immunotherapy is implemented. The article you have read has been submitted for RACE approval for 1 hour of continuing education credit and will be opened for enrollment when approval has been received. To receive credit, take the approved test online for free at vetfolio.com/journal-ce . Free registration on VetFolio.com is required. Questions and answers online may differ from those below. Tests are valid for 2 years from the date of approval. CONTINUING EDUCATION NOTE Questions online may differ from those here; answers are available once CE test is taken at vetfolio.com/journal-ce . Tests are valid for 2 years from date of approval.