Today's Veterinary Practice

NOV-DEC 2018

Today's Veterinary Practice provides comprehensive information to keep every small animal practitioner up to date on companion animal medicine and surgery as well as practice building and management.

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NexGard ® (afoxolaner) is the only product approved by the FDA for the prevention of infections that cause Lyme disease in dogs as a result of killing black-legged ticks. NEW CLAIM! is the only product approved by the FDA for is the only product approved by the FDA for is the only product approved by the FDA for Take a bite out of Lyme. NexGard ® is a registered trademark, and FRONTLINE VET LABS TM is a trademark, of Merial. All other trademarks are the property of their respective owners. ©2018 Merial, Inc., Duluth, GA. All rights reserved. PET-0786-NEX0918. NexGard is a Merial product. Merial is now part of Boehringer Ingelheim. IMPORTANT SAFETY INFORMATION: NexGard is for use in dogs only. The most frequently reported adverse reactions include vomiting, pruritus, lethargy, diarrhea and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, see the full prescribing information or visit www.NexGardForDogs.com. The ability of NexGard (afoxolaner) to prevent the transmission of Borrelia burgdorferi by killing infected ticks • The study evaluated two groups of dogs: an untreated control group and a NexGard-treated group. • The dogs in the treated group received NexGard on day 0. • All dogs were: - Infested with ~50 adult Ixodes scapularis ticks (with a B. burgdorferi infection rate of 63.1%) on day 28. - Tested using Lyme Quant C6® and SNAP® 4DX® on days 48, 62, 76, 90, and 102. - Tested for the presence of B. burgdorferi DNA via PCR testing. Skin biopsies collected on day 104. Detection of Borrelia burgdorferi infection Untreated Control Group NexGard-treated Group Lyme Quant C6 & SNAP 4DX ALL dogs tested positive ALL dogs tested negative ALL dogs tested positive PCR ALL dogs tested negative 100% PROTECTED Proven Results against B. burgdorferi transmission 3 Straight from the CAPC: "Nationwide, dogs exposed to the agent of Lyme disease are continuing to be discovered in areas outside recognized endemic regions." 2 LIGHT ACTIVITY HEAVY ACTIVITY Lyme disease is spreading LYME DISEASE - CAPC FORECAST According to the CAPC Parasite Prevalence maps, Lyme disease is the most commonly diagnosed tick-borne disease in dogs in the US. 1 It's a debilitating illness that can be diffi cult to diagnose and treat – but easy to prevent in dogs.

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