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Issue link: http://todaysveterinarypractice.epubxp.com/i/38074
TODAY’S VETERINARY RESEARCH PEER REVIEWED Contrast-Enhanced Ultrasonography for Characterization of Liver Nodules Cintia R. Oliveira, DVM, MS; Nathalie Rademacher, DrMedVet, Diplomate ECVDI & ACVR; and Lorrie Gaschen, DVM, PhD, Diplomate ECVDI Detection and characterization of liver tumors represents a diagnostic imaging challenge in both human and veterinary medicine. R outine gray-scale B-mode ultrasonography is sen- sitive for detecting focal disease in the liver but is nonspe- cific. It is not possible to discrimi- nate between benign lesions and malignancies in most instances because both may have similar echo patterns.1 The purpose of this study was to: UÊ ÃÃiÃÃÊ ÌhiÊ ÃinÃiÌiÛiÌÞ]Ê Ã«iVi- viViÌÞ]Ê >n`Ê >VVÕÀ>VÞÊ ovÊ Von- trast-enhanced ultrasonogra- phy (CEUS) using a second- generation agent containing «iÀvlÕoÀo«Ào«>niÊ bms.com) for differentiation between benign and malig- nant liver lesions in dogs UÊ iÃVÀiLiÊ >n`Ê Vom«>ÀiÊ ÌhiÊ CEUS vascular morphology and enhancement patterns of primary and metastatic lesions. 56 Today’s Veterinary Practice July/August 2011 STUDY OVERVIEW r 5IJT TUVEZ BJNFE UP BTTFTT UIF WBTDVMBS NPSQIPMPHZ BOE QIBTFT PG FOIBODFNFOU PG IFQBUJD OPEVMFT VTJOH B QFSGMVPSPQSPQBOF VMUSBTPVOE DPOUSBTU BHFOU UP EJGGFSFOUJBUF NBMJHOBOU GSPN CFOJHO MFTJPOT r #FOJHO MFTJPOT XFSF JTPFDIPJD XJUI UIF TVSSPVOEJOH MJWFS EVSJOH UIF QPSUBM QIBTF JO BMM CVU PG MFTJPOT r .BMJHOBOU OPEVMFT XFSF IZQPFDIPJD UP TVSSPVOEJOH MJWFS QBSFODIZNB EVSJOH UIF QPSUBM QIBTF PO $&64 JO BMM CVU EPH *O BEEJUJPO BMM NBMJHOBOU OPEVMFT TIPXFE JOUSBMFTJPOBM WFTTFMT EVSJOH UIF QPSUBM QIBTF r " TNBMMFS OVNCFS PG NFUBTUBUJD MFTJPOT IBE BEEJUJPOBM QFSJQIFSBM GFFEJOH WFTTFMT FWJEFOU EVSJOH UIF BSUFSJBM QIBTF UIBU XFSF OPU QSFTFOU JO QSJNBSZ OFPQMBTNT 5IFTF GFBUVSFT XFSF BCTFOU JO BMM CFOJHO MFTJPOT FYDFQU GPS EJBHOPTFE BT OFDSPUJD r 5IF QSFTFODF PG OFDSPTJT XJUIJO B MJWFS OPEVMF NBZ QPTF EJGGJDVMUZ GPS UIF EJGGFSFOUJBUJPO PG CFOJHO GSPN NBMJHOBOU OPEVMFT iviniÌÞ]Ê r "MM IFQBUJD NBTTFT EJBHOPTFE BT IFQBUPDFMMVMBS DBSDJOPNB XFSF IZQPFDIPJD UP TVSSPVOEJOH MJWFS QBSFODIZNB EVSJOH UIF QPSUBM QIBTF )PXFWFS BTTFTTNFOU PG MBSHF NBTTFT XJUI $&64 NBZ OPU CF JOEJDBUFE CFDBVTF PG UIFJS UFOEFODZ UP IBWF OFDSPUJD DFOUFST UIBU XPVME BQQFBS BT SFHJPOT PG IZQPQFSGVTJPO BOE UIFSFGPSF DPVME CF NJTEJBHOPTFE BT NBMJHOBOU /FDSPUJD MFTJPOT IBWF BCTFOU PS QPPS WBTDVMBS TVQQMZ BOE JO UIJT TUVEZ XFSF IZQPFDIPJD JO UIF BSUFSJBM QIBTF XIJDI XBT OPOEJTDSJNJOBUPSZ CFUXFFO CFOJHO BOE NBMJHOBOU MFTJPOT r 5IF SFTVMUT PG UIJT TUVEZ BSF JO BDDPSEBODF XJUI QSFWJPVT TUVEJFT JO XIJDI $&64 TIPXFE IJHI TFOTJUJWJUZ BOE TQFDJGJDJUZ UP DIBSBDUFSJ[F IFQBUJD OPEVMFT 3-6