Today's Veterinary Practice

MAR-APR 2018

Today's Veterinary Practice provides comprehensive information to keep every small animal practitioner up to date on companion animal medicine and surgery as well as practice building and management.

Issue link:

Contents of this Issue


Page 40 of 95

35 MARCH/APRIL 2018 ● TVPJOURNAL.COM FEATURES system. Prolonged fluid replacement is often poorly tolerated by patients with CKD because of poor renal perfusion and a limited ability to excrete surplus volume. ■ Is the patient eating and drinking enough? A good appetite supports a good quality of life. Find palatable diets, avoid high-salt foods, and try appetite stimulants. In cats with concurrent cardiac and renal disease, feeding tubes may improve nutritional status and make administering multiple medications easier. TAKEAWAYS: ■ When you diagnose pathology in the cardiovascular or renal system, especially in an older animal, look for concurrent disease in the other system. ■ If both systems are involved, focus your management strategy on the system causing the most severe clinical signs. ■ Because therapy for one system may be counterproductive for the other, monitor the patient closely. ■ According to history, physical examination findings, and diagnostic test results, adjust therapy (eg, fluids, electrolytes, drug dosages) as needed. References 1. Pouchelon JL, Atkins CE, Bussadori C, et al. Cardiovascular-renal axis disorders in the domestic dog and cat: a veterinary consensus statement. J Small Anim Pract 2015;56(9):537-552. 2. Reynolds BS, Lefebvre HP. Feline CKD: pathophysiology and risk factors—what do we know? J Feline Med Surg 2013;15(Suppl 1):S3-S14. 3. Hsu A, Kittleson MD, Paling A. Investigation into the use of plasma NT-proBNP concentration to screen for feline hypertrophic cardiomyopathy. J Vet Cardiol 2009;11(Suppl 1):S63-S70. 4. Fox PR, Rush JE, Reynolds CA, et al. Multicenter evaluation of plasma N-terminal probrain natriuretic peptide (NT-pro BNP) as a biochemical screening test for asymptomatic (occult) cardiomyopathy in cats. J Vet Intern Med 2011;25(5):1010-1016. 5. Lalor SM, Connolly DJ, Elliott J, Syme HM. Plasma concentrations of natriuretic peptides in normal cats and normotensive and hypertensive cats with chronic kidney disease . J Vet Cardiol 2009;11(Suppl 1):S71-S79. 6. Bijsmans ES, Jepson RE, W heeler C, et al. Plasma N-terminal probrain natriuretic peptide, vascular endothelial growth factor, and cardiac troponin I as novel biomarkers of hypertensive disease and target organ damage in cats. J Vet Intern Med 2017;31(3):650-660. 7. International Renal Interest Society. IRIS guidelines. guidelines/index.html. Accessed April 2017. 8. Relford R, Roberston J, Clements C. Symmetric dimethylarginine: improving the diagnosis and staging of chronic kidney disease in small animals. Vet Clin Sm Anim 2016;46(6):941-960. 9. Atkins C, Bonagura J, Ettinger S, et al. Guidelines for the diagnosis and treatment of canine chronic valvular heart disease. J Vet Intern Med 2009;23(6):1142-1150. 10. Brown S, Elliott J, Francey T, et al. Consensus recommendations for standard therapy of glomerular disease in dogs. J Vet Intern Med 2013;27(Suppl 1:S27-S43. 11. Lefebvre HP, Brown SA, Chetboul V, et al. Angiotensin-converting enzyme inhibitors in veterinary medicine. Curr Pharmaceut Design 2007;13(13):1347-1361. 12. Rush J, Freeman LM, Brown DJ, et al. The use of enalapril in the treatment of feline hypertrophic cardiomyopathy. JAAHA 1998;34(1):38-41. 13. Gordon SG, Cote E. Pharmacotherapy of feline cardiomyopathy: chronic management of heart failure. J Vet Cardiol 2015;17(Suppl 1):S159-S172. 14. MacGregor JM, Rush JE, Laste NJ, et al. Use of pimobendan in 170 cats (2006-2010). J Vet Cardiol 2011;13(4):251-260. 15. Gordon SG, Saunders AB, Roland RM, et al. Effect of oral administration of pimobendan in cats with CHF. JAVMA 2012;241(1):89-94. 16. Reina-Doreste Y, Stern JA, Keene BW, et al. Case-control study of the effects of pimobendan on survival time in cats with hypertrophic cardiomyopathy and congestive heart failure. JAVMA 2014;245(5):534- 539. 17. Davis H, Jensen T, Johnson A, et al. 2013 AAHA/AAFP fluid therapy guidelines for dogs and cats. JAAHA 2013;49(3):149-159. 18. Brown S, Atkins C, Bagley R, et al. Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med 2007;21(3):542-558. 19. Taylor SS, Sparkes AH, Briscoe K, et al. ISFM consensus guidelines on the diagnosis and management of hypertension in cats. J Fel Med Surg 2017;19(3):288-303. 20. Syme HM, Barber PJ, Markwell PJ, et al. Prevalence of systolic hypertension in cats with chronic renal failure at initial evaluation. JAVMA 2002;220(12):1799-1804. 21. Jepson RE, Syme HE, Elliott J. Plasma renin activity and aldosterone concentrations in hypertensive cats with and without azotemia and in response to treatment with amlodipine besylate. J Vet Intern Med 2014;28(1):144-153. 22. Chetboul V, Lefebvre HP, Pinhas C, et al. Spontaneous feline hypertension: clinical and echocardiographic abnormalities, and survival rate. J Vet Intern Med 2003;17(1):89-95. 23. Atkins CE, Rausch WP, Gardner SY, et al. The effect of amlodipine and the combination of amlodipine and enalapril on the renin-angiotensin- aldosterone system in the dog. J Vet Pharmacol Ther 2007;30(5):394-400. Audrey K. Cook Audrey K. Cook is a Diplomate of both ACVIM and ECVIM and is Board Certified in Feline Practice (ABVP). She is currently an associate professor of small animal internal medicine at Texas A&M, with particular interests in endocrinology, gastroenterology, feline medicine and endoscopy. Dr. Cook routinely speaks at national meetings and is a recipient of the Texas A&M University Distinguished Achievement Award in Teaching. Ashley B. Saunders Ashley B. Saunders, DVM, Diplomate ACVIM (Cardiology), is an associate professor of cardiology at Texas A&M University's College of Veterinary Medicine and Biomedical Sciences. Her interests include interventional cardiology and advanced imaging, heart failure management, and innovative teaching. She is a Montague Center for Teaching Excellence Scholar and has been awarded a Texas A&M University Distinguished Achievement Award in Teaching.

Articles in this issue

Links on this page

Archives of this issue

view archives of Today's Veterinary Practice - MAR-APR 2018