Today's Veterinary Practice

TVP_JUL-AUG2018

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induced by CKD may play a more important role in muscle wasting seen in patients eating a therapeutic renal diet. Until further evidence is available, dogs with azotemic or proteinuric CKD will benefit from a therapeutic diet designed for renal disease and every effort, including use of feeding tubes, should be made to maintain adequate caloric intake. References 1. Jacob F, Polzin DJ, Osborne CA, et al. Clinical evaluation of dietary modification for treatment of spontaneous chronic renal failure in dogs. JAVMA 2002;220(8):1163-1170. 2. Polzin DJ, Osborne CA, Hayden DW, Stevens JB. Influence of reduced protein diets on morbidity, mortality, and renal function in dogs with induced chronic renal failure. Am J Vet Res 1984;45(3):506-517. 3. Polzin DJ, Osborne CA, Stevens JB, Hayden DW. Influence of modified protein diets on the nutritional status of dogs with induced chronic renal failure. Am J Vet Res 1983;44(9):1694-1702. 4. Ahmed MS, Abed M, Voelkl J, Lang F. Triggering of suicidal erythrocyte death by uremic toxin indoxyl sulfate. BMC Nephrol 2013;14:244. 5. Bricker NS, Morrin PA, Kime SW. The pathologic physiology of chronic Bright's disease. An exposition of the "intact nephron hypothesis". J Am Soc Nephrol 1997;8(9):1470-1476. 6. Valli VE, Baumal R, Thorner P, et al. Dietary modification reduces splitting of glomerular basement membranes and delays death due to renal failure in canine X-linked hereditary nephritis. Lab Invest 1991;65(1):67-73. 7. Burkholder WJ, Lees GE, LeBlanc AK, et al. Diet modulates proteinuria in heterozygous female dogs with X-linked hereditary nephropathy. J Vet Intern Med 2004;18(2):165-175. 8. Zatelli A, Roura X, D'Ippolito P, et al. The effect of renal diet in association with enalapril or benazepril on proteinuria in dogs with proteinuric chronic kidney disease. Open Vet J 2016;6(2):121-127. 9. National Research Council. Nutrient Requirements of Dogs and Cats. Washington, DC: The National Academies Press; 2006. 10. Rutherford WE, Bordier P, Marie P, et al. Phosphate control and 25-hydroxycholecalciferol administration in preventing experimental renal osteodystrophy in the dog. J Clinic Invest 1977;60:332-341. 11. Finco DR, Brown SA, Crowell WA, et al. Effects of phosphorus/calcium- restricted and phosphorus/calcium-replete 32% protein diets in dogs with chronic renal failure. Am J Vet Res 1992;53(1):157-163. 12. Brown SA, Brown CA, Crowell WA, et al. Beneficial effects of chronic administration of dietary omega-3 polyunsaturated fatty acids in dogs with renal insufficiency. J Lab Clin Med 1998;131(5):447-455. 13. Cline M. Nutritional management of chronic kidney disease in cats & dogs. Todays Vet Pract 2016;6(2):58-66. Angela Witzel Rollins Dr. Angela Witzel Rollins performed her DVM, PhD, and residency training at the University of Tennessee College of Veterinary Medicine. Dr. Witzel is a Diplomate and former President and Chair of the Board for the American College of Veterinary Nutrition. She is also a Clinical Associate Professor of Nutrition at the University of Tennessee Veterinary Medical Center. Her areas of research interest include adipose hormones, body composition, and obesity management. Banfield.com/Careers #BanfieldLife Now hiring talented veterinary professionals. Join our team of cool cats today. We think you're the cat's MEOW ┬ęBanfield 2018.04

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